diff --git a/Content.Server/Chemistry/Components/MeleeChemicalInjectorComponent.cs b/Content.Server/Chemistry/Components/MeleeChemicalInjectorComponent.cs
index 4b855f759a..2042c1d212 100644
--- a/Content.Server/Chemistry/Components/MeleeChemicalInjectorComponent.cs
+++ b/Content.Server/Chemistry/Components/MeleeChemicalInjectorComponent.cs
@@ -15,6 +15,12 @@ namespace Content.Server.Chemistry.Components
         [DataField("transferEfficiency")]
         private float _transferEfficiency = 1f;
 
+        /// <summary>
+        /// Whether this will inject through hardsuits or not.
+        /// </summary>
+        [DataField("pierceArmor"), ViewVariables(VVAccess.ReadWrite)]
+        public bool PierceArmor = true;
+
         /// <summary>
         ///     Solution to inject from.
         /// </summary>
diff --git a/Content.Server/Weapons/Melee/MeleeWeaponSystem.cs b/Content.Server/Weapons/Melee/MeleeWeaponSystem.cs
index 7d8c0873e9..c354a82bcc 100644
--- a/Content.Server/Weapons/Melee/MeleeWeaponSystem.cs
+++ b/Content.Server/Weapons/Melee/MeleeWeaponSystem.cs
@@ -15,7 +15,10 @@ using Content.Shared.Database;
 using Content.Shared.FixedPoint;
 using Content.Shared.Hands.Components;
 using Content.Shared.IdentityManagement;
+using Content.Shared.Inventory;
+using Content.Shared.Popups;
 using Content.Shared.StatusEffect;
+using Content.Shared.Tag;
 using Content.Shared.Verbs;
 using Content.Shared.Weapons.Melee;
 using Content.Shared.Weapons.Melee.Events;
@@ -35,8 +38,10 @@ public sealed class MeleeWeaponSystem : SharedMeleeWeaponSystem
     [Dependency] private readonly BloodstreamSystem _bloodstream = default!;
     [Dependency] private readonly ContestsSystem _contests = default!;
     [Dependency] private readonly ExamineSystem _examine = default!;
+    [Dependency] private readonly InventorySystem _inventory = default!;
     [Dependency] private readonly LagCompensationSystem _lag = default!;
     [Dependency] private readonly SolutionContainerSystem _solutions = default!;
+    [Dependency] private readonly TagSystem _tag = default!;
 
     public override void Initialize()
     {
@@ -254,6 +259,13 @@ public sealed class MeleeWeaponSystem : SharedMeleeWeaponSystem
             if (Deleted(entity))
                 continue;
 
+            // prevent deathnettles injecting through hardsuits
+            if (!comp.PierceArmor && _inventory.TryGetSlotEntity(entity, "outerClothing", out var suit) && _tag.HasTag(suit.Value, "Hardsuit"))
+            {
+                PopupSystem.PopupEntity(Loc.GetString("melee-inject-failed-hardsuit", ("weapon", owner)), args.User, args.User, PopupType.SmallCaution);
+                continue;
+            }
+
             if (bloodQuery.TryGetComponent(entity, out var bloodstream))
                 hitBloodstreams.Add((entity, bloodstream));
         }
diff --git a/Resources/Locale/en-US/weapons/melee/melee.ftl b/Resources/Locale/en-US/weapons/melee/melee.ftl
new file mode 100644
index 0000000000..ad18c43121
--- /dev/null
+++ b/Resources/Locale/en-US/weapons/melee/melee.ftl
@@ -0,0 +1 @@
+melee-inject-failed-hardsuit = Your {$weapon} cannot inject through hardsuits!
diff --git a/Resources/Prototypes/Entities/Clothing/OuterClothing/armor.yml b/Resources/Prototypes/Entities/Clothing/OuterClothing/armor.yml
index e15cfebf98..a270f4a959 100644
--- a/Resources/Prototypes/Entities/Clothing/OuterClothing/armor.yml
+++ b/Resources/Prototypes/Entities/Clothing/OuterClothing/armor.yml
@@ -163,6 +163,9 @@
   - type: ExplosionResistance
     damageCoefficient: 0.8
   - type: GroupExamine
+  - type: Tag
+    tags:
+    - Hardsuit
 
 - type: entity
   parent: ClothingOuterBaseLarge
diff --git a/Resources/Prototypes/Entities/Clothing/OuterClothing/base_clothingouter.yml b/Resources/Prototypes/Entities/Clothing/OuterClothing/base_clothingouter.yml
index af41be3c40..aed8e69035 100644
--- a/Resources/Prototypes/Entities/Clothing/OuterClothing/base_clothingouter.yml
+++ b/Resources/Prototypes/Entities/Clothing/OuterClothing/base_clothingouter.yml
@@ -74,6 +74,9 @@
     containers:
       toggleable-clothing: !type:ContainerSlot {}
   - type: GroupExamine
+  - type: Tag
+    tags:
+    - Hardsuit
 
 - type: entity
   abstract: true
diff --git a/Resources/Prototypes/Entities/Clothing/OuterClothing/suits.yml b/Resources/Prototypes/Entities/Clothing/OuterClothing/suits.yml
index 5ec3c1ebaf..8254b3e91d 100644
--- a/Resources/Prototypes/Entities/Clothing/OuterClothing/suits.yml
+++ b/Resources/Prototypes/Entities/Clothing/OuterClothing/suits.yml
@@ -18,6 +18,9 @@
   - type: ExplosionResistance
     damageCoefficient: 0.65
   - type: GroupExamine
+  - type: Tag
+    tags:
+    - Hardsuit
 
 - type: entity
   parent: ClothingOuterEVASuitBase
diff --git a/Resources/Prototypes/Entities/Objects/Consumable/Food/produce.yml b/Resources/Prototypes/Entities/Objects/Consumable/Food/produce.yml
index 5910191b36..f0462227ce 100644
--- a/Resources/Prototypes/Entities/Objects/Consumable/Food/produce.yml
+++ b/Resources/Prototypes/Entities/Objects/Consumable/Food/produce.yml
@@ -133,6 +133,7 @@
   - type: MeleeChemicalInjector
     transferAmount: 6 #To OD someone you would need 2 nettles and about 6-7 hits, the DOT is likely to crit them if they are running away with almost no health
     solution: food
+    pierceArmor: false
   - type: Extractable
     grindableSolutionName: food
 
diff --git a/Resources/Prototypes/tags.yml b/Resources/Prototypes/tags.yml
index f7870ccdc6..8b4550abc1 100644
--- a/Resources/Prototypes/tags.yml
+++ b/Resources/Prototypes/tags.yml
@@ -293,6 +293,9 @@
 - type: Tag
   id: Handcuffs
 
+- type: Tag
+  id: Hardsuit # Prevent melee injectors that can't penetrate hardsuits from injecting the wearer (nettles)
+
 - type: Tag
   id: Head